AIS Biotech wins the i-LAB 2023 competition
The AIS BIOTECH start-up, resulting from the work of Cermav, is laureate of the i-Lab 2023 Competition of BPI France.
Antoine DESIGAUX’s thesis defense on June 27th, 2023
Antoine DESIGAUX completed his thesis at Cermav under the co-supervision of Laurent HEUX (CNRS Research Director) and Sonia MOLINA – BOISSEAU (Université Grenoble Alpes Senior lecturer). It is entitled « Development as well as mechanical and structural characterization of an anisotropic elastomer reinforced by cellulose microfibrils. ».
Creation of the new start-up resulting from the work of Cermav, AIS Biotech
AIS Biotech relies on innovative, efficient, industrializable biotechnology with low environmental impact, to develop a new class of anti-infective biomedicines. Click on the title for more information.
Structural Glycoscience Summer School 2023 in Grenoble (from June 5th to 7th, 2023)
Register at https://glycoalps.univ-grenoble-alpes.fr/glyco-club/glyco-club-s-activities/structural-glycoscience-summer-school-2023-886248.kjsp
Supramolecular carbohydrate-based hydrogels from oxidative hydroxylation of amphiphilic β-C-glycosylbarbiturates and α-glucosidaseinduced hydrogelation
The team “Self-assembly of Glycopolymers” of CERMAV has developed a new family of sugar derivatives through an eco-responsible process which is able to self-assemble into hierarchical glyconanostructures to ultimately gel water and the gelation can be triggered by the action of a glycosidase. Click on the title for more information.
Helical inclusion complexes of amylose with aromatic compounds: Crystallographic evidence for new V-type allomorphs
The morphology and crystal structure of three new inclusion complexes of amylose with small aromatic molecules were described, thus widening the family of V-amylose allomorphs that may form when starch is processed in the presence of various ingredients and additives.
Click on the title for more information.
Deciphering GAGs: a new way of sequencing polysaccharides
In this publication involving Bernard Priem, Lecturer at the University of Grenoble Alpes, the authors propose an effective and robust approach based on passage through protein nanopores, to decipher the structure of complex bioactive polysaccharides, GAGs. Click on the title for more information.
Malgorzata Sulewska thesis defense on January 13th, 2023
Malgorzata Sulewska completed her thesis at Cermav under the co-direction of Bernard Priem (Grenoble Alpes University) and Rita Gerardy-Schahn (Hannover Medical School). It is entitled “Biosynthesis, Depolymerization, Detection, and Analysis of Glycosaminoglycans with a Focus on Heparosan”.
François Bru thesis defense on January 20th, 2023
François Bru completed his thesis at Cermav under the supervision of Laurent Heux, CNRS Research Director, entitled “Hydrophobization of 100% cellulosic materials for single-use packaging”. He focuses on hydrophobization of cellulosic materials. Click on the title for more information.
Hijacking the Peptidoglycan Recycling Pathway of Escherichia coli to Produce Muropeptides
Muropeptides are short peptidoglycan fragments released from the cell wall of bacteria as part of their metabolism or as a result of biological stresses, in which they play a major role in the induction of antibiotic resistance. In order to better understand these processes, we developed a new synthetic approach which combines synthetic biology and glycochemistry to prepare Gram (–) and Gram (+) muropeptides. Click on the title for more information.
Hong LI thesis defense on December 06th, 2022
Hong LI completed his thesis at Cermav under the supervision of Redouane Borsali, CNRS Research Director. it is entitled “Self-assembly of carbohydrate-based brush-like block copolymers: colored biomaterials and photonic crystals”. Click on the title for more information.
Shun Yao thesis defense on November 16th, 2022
Shun Yao completed his thesis at Cermav under the supervision of Sami Halila, CNRS researcher. It is entitled “Syntheses, properties and applications of glyco-hydrogelators”. Click on the title for more information.
Biotechnological production of sialylated solid lipid microparticles as inhibitors of influenza A virus infection
In this publication in collaboration with the CIRI – International Center for Research in Infectiology (UMR Université Lyon 1, Inserm, CNRS and ENS Lyon), we show a new biotechnological approach for the elaboration of sialylated microparticles, capable of luring Influenza viruses, responsible for human flu. Click on the title for more information.
Hamed AHMADI-NOHADANI thesis defense on December 16th, 2022
Hamed AHMADI-NOHADANI completed his thesis at Cermav under the supervision of Issei Otsuka, CNRS Researcher at Cermav. It is entitled “Electrospinning Light-Harvesting Cellulose Nanofibers”.
The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases
A study combining mutagenesis experiments, high-resolution X-ray diffraction with thiosugars and molecular modeling has revealed the molecular basis for the specificity and processivity of an enzyme of the GH3 family of glycoside hydrolases.
Interview with Anne Imberty in Le Monde Science
Anne Imberty, CNRS Research Director at Cermav, was interviewed in Le Monde Sciences about Glycosciences.
Simon Coninx thesis defense on October 24th, 2022
Simon Coninx completed his thesis at Cermav under the supervision of Rachel Auzely, Professor at Université Grenoble Alpes. It is entitled “Nanogels based on boron-rich glycosaminoglycans for the multi-modal treatment of cancer”. Click on the title for more information.
The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3
Choanoflagellate lectin SaroL-1 binds to cancer-related α-galactosylated epitopes and can be toxic to cancer cells through a pore-formation mechanism. Click on the title for more information.
Press article on the Carbogel project led by Sami Halila
The Carbogels project led to patent application for a new class of organogelator with adjustable rheological properties for cosmetics and dermopharmacy. Click on the title for more information.
Multifaceted Computational Modeling In Glycoscience
This review comprehensively presents all the numerical simulation methods to cover the different levels of structural organization of complex glycans and polysaccharides and the range of their interactions with proteins. Click on the title for more information.
Eleventh Erwin Felix Lewy Bertaut Prize to Dr. Lukáš Gajdos
Lukáš Gajdos completed his thesis at Cermav under the co-direction of Anne Imberty (CNRS Research Director) and the Laue-Langevin Institute in Grenoble, France. Click on the title for more information.
Dylan Jabeguero thesis defense on June 30th, 2022
Dylan Jabeguero completed his thesis at Cermav under the supervision of Christelle BRETON (Professor at University Grenoble Alpes). It is entitled “Engineering and applications of glycosyltransferases for synthetic glycobiology: Two galactosyltransferases, MGD1 and LgtC, as case studies”. Click on the title for more information.
Simona Notova thesis defense on June 29th, 2022
Simona Notova completed her thesis at Cermav under the supervision of Anne Imberty (CNRS Research Director). It is entitled “Engineering of neo-lectins and Janus lectins”. Click on the title for more information.
Publication of the book “Essential Glyocobioloy fourth edition” (available free of charge)
Cermav participated in the writing of 3 articles of this book which is considered as the bible of glycobiologists. Click on the title for more information.
