Season’s Greeting
Cermav wishes you a happy holidays!
GAG-DB, the New Interface of the Three-Dimensional Landscape of Glycosaminoglycans
Glycosaminoglycans (GAGs) are complex linear polysaccharides. GAG-DB is a curated database that classifies the three-dimensional features of the six mammalian GAGs (chondroitin sulfate, dermatan sulfate, heparin, heparan sulfate, hyaluronan, and keratan sulfate) and their oligosaccharides complexed with proteins. GAG-DB provides detailed information on GAGs, their bound protein ligands, and features their interactions using several open access applications. Binding covers interactions between monosaccharides and protein monosaccharide units and the evaluation of quaternary structure. Click on the title for more information.
Polymorphism of V-amylose complexed with aliphatic diols
We have published an article in the journal Polymer about the structure of inclusion compounds prepared by crystallizing amylose in the presence of a series of diols. Several molecular models have been proposed based on electron and X-ray diffraction data, and structural transitions have been identified during the drying of the crystals. Click on the title for more information.
Misincorporation of Galactose by Chondroitin Synthase of Escherichia coli K4: From Traces to Synthesis of Chondbiuronan, a Novel Chondroitin-Like Polysaccharide
We published an article in the journal BioMolecules dealing with the synthesis of chondroitin in a recombinant strain of Escherichia coli. The study points out the fact that in absence of UDP-GalNAc which is one of the enzymatic precursors of chondroitin synthesis, chondroitin synthase KfoC incorporates galactose leading to the synthesis of a new polysaccharide named chondbiuronan. Click on the title for more information.
Nanocellulose based-material for wound dressing
A review article is presented by Clémentine Darpentigny and Bruno Jean, taking up elements of Clémentine Darpentigny’s thesis. It aims to provide an overview of cellulose-based nanomaterials and their potential use for wound dressing applications.
PhD Glyco@Alps symposium day
Cermav will participate in the PhD Glyco @ Alps symposium day. Click on the title to find out more.
