Centre de recherches sur les macromolécules végétales
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Dania Martínez-Alarcón completed her thesis within the framework of the European network PhD4GlycoDrug. It was co-directed by Annabelle Varrot (Director of Research CNRS, in our lab) and Roland Pieters (Utrecht University in the Netherlands). The subject of her thesis is the following : "Characterization of lectins from emergin fungi and identification from fungal extracts". Click on the title for more information.
Maxime Leprince completed his thesis in co-supervision between our laboratory (under the co-supervision of Prof. Rachel Auzély) and the CEA - Department of Biology and Health Technologies "DTBS", Chemistry, Sensors and Biomaterials laboratory "L2CB" (under the co-supervision of Dr Isabelle Texier-Nogue). The subject of his thesis is the following "Design of polysaccharide-based conductive inks and hydrogels for the development of controllably biodegradable bioelectronics devices". Click on the title to access the summary.
This thesis was completed in our laboratory, under the supervision of Dr. Yoshiharu NISHIYAMA. The subject is: "Preparation of cellulose oligomers by acid hydrolysis." Click on the title for more information.
Advancements in high-performance computing have allowed molecular simulation methods to play a more substantial role in supporting experiments and transcend such mandate to guide experimental design and lead autonomously scientific discovery. This review presents the foundations underlying the multiscale molecular simulations methods, from atomistic to coarse-grained, used in complex carbohydrate research. The applications to glycan and glycoconjugates, polysaccharides, proteins-glycans interactions,… illustrate the relevance of computer simulations to the field of glycoscience. Click on the title for more information.
Many biologically-active compounds, such as drugs, agrochemicals, food additives, etc. have chiral structures (like right- and left-hands) and their physiological properties usually depend on their chirality. In this study, cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC), known as one of the most versatile chiral selectors packed in columns for chiral chromatography, is electrospun for the first time to fabricate an enantioselective membrane toward efficient chiral resolutions. We believe that such a novel electrospun cellulosic membrane having both the enantioselective permeation property and the capacity to be used in pressure-driven filtration processes is a significant step forward toward large-scale chiral resolutions. Click on the title for more information.
We are publishing a new review on electrospun polysaccharide textiles for biomedical applications, in a new open access journal entitled Textiles, which covers studies in the field of textile science and industry. Click on the title for more information.